The latest news doing the rounds is that majority of the people who suffer from infertility have undiagnosed celiac disease or gluten intolerance. The majority of the studies stating this have been carried out in Europe, while just 2 studies have been taken place in the United States. In order to further validate this finding, a research was carried out by the Peter Green’s group at Columbia to see whether or not there existed any relationship between celiac disease, gluten intolerance and the infertile population. The results of the research were published in The Journal of Reproductive Medicine.
The population understudy included the 188 women aged 25-39, and who had been suffering from infertility issues for the past one year. Various tests for celiac disease and gluten intolerance were conducted, which included serological screening for transglutaminase and endomysial antibodies and measurement of total IgA and both IgA and IgG antigliadin antibodies. Results revealed that 4 out of 188 women were diagnosed with celiac disease, which means that 2.1% of women in this given population tested positive for celiac disease. A further sub group analysis of women with unexplained fertility revealed a prevalence of 5.9%, which was statistically significant.
The 4 women who were diagnosed with celiac disease, showed symptoms of abdominal distention, and also had increased prevalence of irritable bowel syndrome. The authors acknowledge that the sample was pretty small and the screening process of the subjects being a voluntary one, it was a selected population. When the 4 women were put on gluten free diet for a period of 10 months, they could successfully conceive and deliver healthy babies.
However, the results draw our attention towards the fact that when women face problems with unexplained infertility then they should always be screened for gluten intolerance or celiac disease.